Poster Presentation Australasian Diabetes in Pregnancy Society Annual Scientific Meeting 2019

Relationship between sleep and snoring and body mass index among women with risk factors for gestational diabetes mellitus at booking: Preliminary findings from a multicentre randomized trial (#73)

David Simmons 1 2 , Lisa Vizza 1 , BillBill Hague 3 , Helena Teede 4 , N Wah Cheung 5 , Emily Hibbert 6 , Christopher Nolan 7 , Michael Peek 8 , Vincent Wong 9 , Jeff Flack 10 , Mark Mclean 11 , Jurgen Harreiter 12 , Alexandra Kautzky-Willer 12
  1. University of Western Sydney, Campbelltown, NSW, Australia
  2. Endocrinology, Campbelltown Hospital, Campbelltown, NSW, Australia
  3. Robinson Research Institute, and Women's and children's Hospital, The University of Adelaide, Adelaide, South Australia, Australia
  4. Monash University, Melbourne, Vic, Australia
  5. Westmead Hospital, Sydney, NSW, Australia
  6. Nepean Hospital, Penrith, NSW, Australia
  7. Canberra Hospital and Australian National University, Canberra, ACT, Australia
  8. Australian National University, Canberra, ACT, Australia
  9. Liverpool Hospital, Liverpool, NSW, Australia
  10. Bankstown-Lidcombe Hospital, Sydney, NSW, Australia
  11. Blacktown Hospital, Blacktown, NSW, Australia
  12. Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria

Aim: To compare the rates of self-reported snoring and insufficient sleep between different booking body mass index (BMI) groups among pregnant women at-risk of gestational diabetes mellitus (GDM) enrolled in the Treatment of Booking Gestational Diabetes Mellitus (TOBOGM) study.

Methods: Pregnant women with risk factors for hyperglycaemia in pregnancy were enrolled at booking (<20 weeks gestation) between June 2017 and May 2019.  Glucose data, kept separate from the database in keeping with the blinded nature of the trial, were not included in this analysis.  Sleep was assessed with the question “How many hours do you sleep per 24 hours on average?”, insufficient sleep with “How many days in the last month have you had the feeling of insufficient sleep?” and snoring with “How many days per week do you snore / are told you snore?”.  World Health Organisation BMI groups were used to define overweight/obesity.

Results: Among 1899 women: mean age 30.8±5.2 years, BMI 29.9±7.3 kg/m2, non-European descent 62.1%, current smokers 6.7%, median gravidity 2, median parity 1.  The prevalence of overweight, obesity classes I-III was 28.0%, 20.6%, 11.9% and 11.1% respectively.  Mean(±SD) duration reported sleep/night was 7.8±1.4 hours, reported median (IQR) days/month with insufficient sleep was 4(1-10), snoring was reported in 35.3%.  The proportion of women reporting at least 8 hours sleep/night dropped across the BMI groups (79.2% to 53.7%, p=0.008), the proportion reporting insufficient sleep >4 days/month increased (43.5% to 63.5%, p<0.001), and the report of any snoring increased (17.4% to 55.0%, p<0.001).  Within BMI groups, there were no differences between women of European and non-European descent women in self-reported sleep duration and snoring, but European descent women were 2.03 (95%CI 1.66-2.47) times more likely to report insufficient sleep.

Conclusion: Preliminary analyses indicate that self-reported insufficient sleep and snoring increase markedly with increasing booking BMI.  Further work is needed to investigate changes as gestation advances and any relationship with glycaemia and adverse pregnancy outcomes.